It’s a strange feeling to be sick and to feel so alone, but for some people, it can feel like life is over.
A new study from the University of Chicago’s Feinberg School of Medicine finds that some patients who experience NPH-like symptoms have a heightened sensitivity to touch, meaning they’re more susceptible to infection.
In a study published today in the journal Science Translational Medicine, researchers examined NPH patients in the United States.
The study found that the people who experienced NPH more frequently, reported more severe infections and higher levels of NPH antibodies.
The researchers then looked at how these patients’ NPH levels changed over time.
Their analysis showed that the higher the NPH status, the more frequently the patients experienced NPL symptoms.
Researchers said their findings could help scientists understand how NPH develops, and could help explain why some people have more severe NPH than others.
“It is possible that this is because NPH is a self-limiting disease,” study author Dr. Jeffrey N. Krim said in a statement.
“In some people it’s not the symptoms but the underlying cause of the NPL, and therefore, this may be why certain NPL patients may have a higher infection burden than others.”
The researchers also discovered that NPH people who had higher levels in their blood were also more likely to develop NPL.
“This suggests that NPL is not a disease of the brain or spinal cord,” Dr. Kram said.
“Rather, NPH involves a pathway from the brain to the spinal cord.”
Krim and his colleagues say that the new findings suggest that the “brain” part of NPL can be controlled, while the “spinal cord” part can be manipulated.
That’s important because NPL causes serious problems in some patients, including chronic headaches and back pain.
The National Institutes of Health is providing grants for the study.